一、 研究方向、目标、内容等基本情况简介
实验室将围绕心力衰竭及相关疾病的基础研究与临床防治开展科学研究，力求通过科学研究去发现及解决临床中的复杂及疑难问题，从而进一步提高对心力衰竭的临床诊治及管理水平；建成一个疑难危重病及慢性病管理的科学研究中心、区域医疗救治中心、人才与技术培训中心，并打造成具有区域医疗中心特色的转化医学研究和人才培养平台，专科的临床、科研、教学水平得到极大的提升，使影响力名列全省前茅并在国内具有一定知名度。
二、 获得经费资助情况
由衡阳市科技局2019年科技计划项目专项经费（10.00万元）资助。
三、 团队成员情况介绍
四、设备设施及科研条件介绍
五、取得的成绩（论文、论著、奖励、成果转化等）
实验室近3年承担科研课题
实验室近3年发表的学术专著和论文
1.Anbo Gao; Jin Zou; Zhenjiang Mao; Hong Zhou*; Gaofeng Zeng（曾高峰）*.SUMO2-mediated SUMOylation of SH3GLB1 promotes ionizing radiation-induced hypertrophic cardiomyopathy through mitophagy activation. European Journal of Pharmacology. IF=5.0，中科院2区，JCR2区，论著.
2. Peng Zhong*, Miao Zhou, Jingjing Zhang, Jianye Peng, Gaofeng Zeng （曾高峰）*, He Huang*. The role of Cold-Inducible RNA-binding protein in respiratory diseases. Journal of Cellular and Molecular Medicine. IF=5.3，中科院2区，JCR2区，综述.
3.Wang Q#, Wu JF#, Zeng YC, Chen K, Wang CX, Yang SQ, Sun NS, Chen H, Duan K, Zeng GF(曾高峰)*. Pyroptosis: a?pro-inflammatory?type?of?cell?death in cardiovascular disease. Clin Chim Acta. IF=3.786，中科院3区，JCR3区，综述.
4. Chen K#, Zhao ZW#, Wang G#, Zou J, Yu XH, Zhang DW, Zeng GF(曾高峰)*, Tang CK*. Interleukin-5 promotes ATP-binding cassette transporter A1 expression through miR-211/JAK2/STAT3 pathways in THP-1-dervied macrophages. Acta BiochimBiophys Sin. IF=3.848，中科院3区，JCR3区，论著.
5. Xiaohan Zheng , Fusang Wang , Juan Zhang, Xiaoli Cui, Fuping Jiang, Nihong Chen, Junshan Zhou, Jinsong Chen （陈劲松）*, Song Lin*, Jianjun Zou*. Using machine learning to predict atrial fibrillation diagnosed after ischemic stroke. International Journal of Cardiology. IF=3.5，中科院2区，JCR2区，论著.
6. Jinsong Chen （陈劲松）*, Yang Liu , Yunyang Liu , Jianye Peng. Resveratrol protects against ox-LDL-induced endothelial dysfunction in atherosclerosis via depending on circ_0091822/miR-106b-5p-mediated upregulation of TLR4. Immunopharmacology and Immunotoxicology. IF=3.3，中科院3区，JCR2区，论著.
7. Shao Ouyang （欧阳劭）, Wei Chen, Zeng Gaofeng, Lei Changcheng, Tian Guoping, Zhu Minyan, Liu Yang, Yang Min, Jiahao Luo. Cyanidin?3?O?β?glucoside protects against pulmonary artery hypertension induced by monocrotaline via the TGF?β1/p38 MAPK/CREB signaling pathway. Molecular medicine reports. IF=3.423，中科院3区，JCR3区，论著.
8. Shao Ouyang (欧阳劭) , Zhi-Xiang Zhou, Hui-Ting Liu, Zhong Ren, Huan Liu, Nian-Hua Deng, Kai-Jiang Tian, Kun Zhou, Hai-Lin Xie, Zhi-Sheng Jiang. LncRNA-mediated Modulation of Endothelial Cells: Novel Progress in the Pathogenesis of Coronary Atherosclerotic Disease. Current medicinal chemistry. IF=4.1，中科院3区，JCR2区，综述.